RIBOZYME AND OMICS
[K Startup Industry Map] bio-healthcare Industry
Just
a few years ago, the bio-healthcare industry was considered a new growth engine
to feed Korea.
If
only the modifier "Bio" was added, the corporate value jumped several
times, and investors came with money.
However,
the market froze hard through the COVID-19 pandemic.
Except
for some fields such as diagnostic kits, the "money line" in the bio
industry has dried up.
This
is because IPO, venture capital (VC) investment, and CB issuance, which are key
funding channels, have been delayed or canceled one after another.
Boronoi,
which was expected to be the "Unicorn Special List No. 1" in March,
withdrew its listing due to low demand forecasts, and Ari-bio, a new dementia
drug R&D company, failed in the technology evaluation for Special Listing
of Technology Growth. Mezzion's stock price fell down sharply due to not
approving of Fontan surgery (heart deformity surgery) treatment by the U.S.
Food and Drug Administration (FDA).
This
phenomenon doesn’t happen only in Korea.
Since
the pandemic, volatility in the global bio-healthcare sector has continued to
expand. However, it is analyzed that this increase in volatility does not stem
from the damage to fundamentals and growth potential of the bio and healthcare
industries.
Analysts
say that investment sentiment has temporarily worsened due to delays in
clinical trials due to COVID-19, interest rate hikes, and falling pipeline
values due to geopolitical risks due to bio companies, whose future value
accounts for most of their corporate value.
Actually,
the global new drug development market is expected to grow by 7.5% annually by
2026 and grow to USD 304.3 billion (about KRW 386 trillion).
According
to Mirae Asset Securities, the number of clinical trials, a barometer of the
new drug development market, recorded 24,914 cases (excluding COVID-19 clinical
trials) as of 2021.
The
digital healthcare market, which has emerged as a future medical system, is
also rapidly expanding.
According
to the Korea International Trade Association, the global digital healthcare
market is expected to grow by nearly 30% annually from $106.3 billion (about
135 trillion won) in 2019 to $639.4 billion (about 810 trillion won) in 2026.
Fortunately,
as the Yoon Seok-yeol government announced plans to actively foster the bio and
healthcare industries and build infrastructure to support biotechnology fields
such as new drug development, the bio industry is gaining momentum.
Bio-healthcare
startups that stand out as they seek to enter overseas markets such as the U.S.
and Europe are also emerging one after another. It introduces bio and healthcare
startups that should be noted.
▶ New drug development
▷ Rznomics' performance is becoming visible
New drug development is the 'flower of the bio industry'. It's not easy, but it's because once you succeed, you get a huge profit. In particular, as global big pharmaceutical companies are actively engaged in open innovation such as JV(Joint Venture), M&A (Merger and Acquisition), licensing, and joint development for new pipeline transfusions, more opportunities are opening up for new drug development start-ups.
Choong-hyun, Kim, an analyst at Mirae Asset Securities, said, "Among the top 30 drugs in the world, 22 have currently expired patents or expired patents. Investment in new drug development is inevitable for new pipeline transfusions, he said. "It is an opportunity for domestic bio companies with competitiveness in new drug development to quantum jump."
Cell and gene
therapy is the most notable field in the recent development of new drugs.
Rznomics is a
new drug development company based on RNA (ribonucleic acid) established by
Seong-wook, Lee, a professor of bio-convergence at Dankook University in 2017.
It is a mechanism by which RNA replacememt enzymes are used to remove target
RNA that causes disease and generate therapeutic RNA in its place. Therapies
are being developed for liver cancer, glioblastoma, Alzheimer's, and hereditary
retinal pigmentation. In the fourth quarter of 2021, it plans to apply for
domestic and U.S. IND (clinical test plan) and enter clinical trials from 2023.
(Extract from the original article)